09. sep., 23:30
vs
Audi Field (Washington, DC, USA)
eastern
| # | Lag | K | V | U | T | GM | IM | +/- | K |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 22 | 16 | 4 | 2 | 47 | 17 | +30 | 52 |
| 2 |  Inter Miami CF | 22 | 12 | 6 | 4 | 56 | 41 | +15 | 42 |
| 3 |  Chicago Fire | 21 | 11 | 4 | 6 | 39 | 28 | +11 | 37 |
| 4 |  New England Revolution | 22 | 11 | 4 | 7 | 36 | 27 | +9 | 37 |
| 5 |  Charlotte FC | 22 | 10 | 5 | 7 | 40 | 32 | +8 | 35 |
| 6 |  FC Cincinnati | 22 | 8 | 7 | 7 | 49 | 51 | -2 | 31 |
| 7 |  New York City FC | 22 | 7 | 7 | 8 | 36 | 31 | +5 | 28 |
| 8 |  New York Red Bulls | 22 | 7 | 5 | 10 | 32 | 46 | -14 | 26 |
| 9 |  Orlando City SC | 22 | 7 | 4 | 11 | 37 | 54 | -17 | 25 |
| 10 |  Toronto FC | 22 | 5 | 10 | 7 | 32 | 38 | -6 | 25 |
| 11 |  D.C. United | 22 | 5 | 10 | 7 | 28 | 36 | -8 | 25 |
| 12 |  Philadelphia Union | 22 | 6 | 6 | 10 | 34 | 39 | -5 | 24 |
| 13 |  Atlanta United | 22 | 6 | 3 | 13 | 25 | 38 | -13 | 21 |
| 14 |  Montreal Impact | 22 | 5 | 6 | 11 | 30 | 46 | -16 | 21 |
| 15 |  Columbus Crew | 22 | 5 | 5 | 12 | 31 | 39 | -8 | 20 |
western
| # | Lag | K | V | U | T | GM | IM | +/- | K |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Vancouver Whitecaps FC | 21 | 13 | 4 | 4 | 48 | 18 | +30 | 43 |
| 2 |  Houston Dynamo | 22 | 12 | 3 | 7 | 30 | 26 | +4 | 39 |
| 3 |  Los Angeles FC | 23 | 10 | 6 | 7 | 36 | 22 | +14 | 36 |
| 4 |  San Jose Earthquakes | 22 | 10 | 4 | 8 | 39 | 33 | +6 | 34 |
| 5 |  Dallas | 22 | 9 | 7 | 6 | 41 | 37 | +4 | 34 |
| 6 |  St. Louis City SC | 22 | 9 | 7 | 6 | 33 | 30 | +3 | 34 |
| 7 |  Colorado Rapids | 22 | 10 | 1 | 11 | 31 | 28 | +3 | 31 |
| 8 |  San Diego | 22 | 8 | 6 | 8 | 40 | 33 | +7 | 30 |
| 9 |  Minnesota United | 22 | 7 | 8 | 7 | 30 | 32 | -2 | 29 |
| 10 |  Real Salt Lake | 21 | 8 | 4 | 9 | 34 | 33 | +1 | 28 |
| 11 |  Portland Timbers | 22 | 8 | 4 | 10 | 39 | 39 | +/-0 | 28 |
| 12 |  Seattle Sounders | 21 | 7 | 5 | 9 | 24 | 29 | -5 | 26 |
| 13 |  Los Angeles Galaxy | 23 | 6 | 8 | 9 | 28 | 35 | -7 | 26 |
| 14 |  Austin FC | 22 | 6 | 6 | 10 | 28 | 41 | -13 | 24 |
| 15 |  Sporting Kansas City | 22 | 4 | 3 | 15 | 20 | 54 | -34 | 15 |